On behalf of the Local Organising and the International Scientific Committees, we warmly invite you to the 41st Annual Meeting of the European Society of Paediatric Infectious Diseases (ESPID), which will take place both online and in Lisbon, Portugal on 8-12 May 2023. We will bring together world-renowned researchers and clinicians for a very exciting multi-faceted programme covering areas that include clinical issues, epidemiology, public health, microbiology, immunology, host-pathogen interactions, genomics, and their interfaces, highlighting more recent progress and also where advances have been more challenging, ESPID is the world's premier paediatric infectious diseases meeting for professionals who want to stay up to date, apply state-of-the art science to clinical care, present their research, reinforce existing and develop new collaborations.